Dr. Lisa Mosconi, an eminent neuroscientist specialising in women’s health.

She holds distinguished roles as an Associate Professor of Neuroscience in Neurology and Radiology at Weill Cornell Medicine. She serves as the Director of the Alzheimer’s Prevention Program at WCM/NewYork-Presbyterian Hospital. Acknowledged by The Times as one of the 17 most influential female scientists, she’s heralded as the “Mona Lisa of Neuroscience” by ELLE International. Additionally, she is a New York Times bestselling author with works like The XX Brain and Brain Food. Continually reshaping our comprehension of brain health and aging, Dr. Mosconi imparts her latest insights in her insightful new book, The Menopause Brain.

Dr. Mosconi’s scholarly pursuits navigate the intersections of cognition and women’s health, spotlighting the pivotal connection between the brain and hormonal regulation—casting menopause not as a conclusion but as a reset.

Fast forward to the most relevant bits by using this guide below…

• 00:00:00 Intro

• 00:01:15 Dr. Mosconi's Background

• 00:03:34 Interest in Neuroscience

• 00:04:37 Move to the United States

• 00:06:14 Gender Disparities in Alzheimer's

• 00:08:27 Historical Context of Women's Health in Science

• 00:15:16 Bikini Medicine

• 00:19:16 Sex Differences in Brain Aging

• 00:22:46 Understanding Menopause

• 00:23:57 Impact of Menopause on the Brain

• 00:25:36 Research Gap in Menopause and Brain Imaging

• 00:26:34 Brain Scans and Menopausal Status

• 00:29:17 Genetic Predisposition to Alzheimer's

• 00:31:57 Sponsor Break

• 00:33:05 Back To Show

• 00:34:31 Apolipoprotein E (APOE) Gene

• 00:38:28 Menopause and Cognitive Changes

• 00:49:16 Evolutionary Perspective on Menopause

• 00:49:35 Brain Scans and Menopausal Changes

• 00:53:43 Menopause and Brain Changes

• 00:55:47 Differential Menopausal Experiences

• 00:56:13 Menopause Types and Health Risks

• 00:58:02 Hysterectomy and Alzheimer's Risk

• 00:58:47 Induced Menopause and Cancer Treatments

• 00:59:52 Understanding Alzheimer's and Dementia

• 01:02:06 Sponsor Break

• 01:03:13 Cardiovascular Health and Dementia

• 01:05:55 Lifestyle and Brain Health

• 01:11:53 Neuro-Nutrition and Brain Health

• 01:17:30 Antioxidant-Rich Foods

• 01:19:35 Supplementation and Nutritional Deficiencies

• 01:21:57 Antioxidants and Brain Health

• 01:23:02 Fiber and Hormonal Health

• 01:24:05 Microbiome and Hormonal Health

• 01:27:47 Exercise Intensity and Brain Health

• 01:32:11 Consistency and Long-Term Impact of Lifestyle Changes

• 01:36:05 Hormone Replacement Therapy and Alzheimer's Risk

• 01:45:07 Hormone Replacement Therapy

• 01:46:30 Estrogen Only Formulations

• 01:49:28 Timing and Type of Hormone Therapy

• 01:50:26 Brain Scans and Designer Estrogen

• 01:54:20 Pharmacological Interventions

• 01:55:41 Diet and Menopause

• 01:57:10 Sleep and Brain Health

• 02:06:18 Baseline Testing

• 02:11:15 Brain Scans and Alzheimer's Prevention Program

• 02:15:12 Media's Relationship to Health Information

• 02:16:16 Social Media and Information Accuracy

• 02:22:08 Scientists and Doctors' Communication Challenges

• 02:23:22 Science Communication and Public Understanding

• 02:23:59 Closing Remarks/Credits